Stem cells can renew themselves and differentiate into a range of specialized cell types, making them fascinating to research and medical care. The stem cells we are using (Umbilical cord-derived stem cells) have unique advantages of easy procurement, absence of risk to donors, no risk of transmitting infections, immediate availability, greater tolerance of human leukocyte antigen (HLA) disparity and no risk of graft-versus-host-disease (GVHD). Human Umbilical Cord-Mesenchymal Stem Cells have shown the potential to differentiate into a variety of cells such as bone, cartilage, adipose, skeletal muscle, cardiomyocyte, endothelium, hepatocyte-like cluster, islet-like cluster, neuron, astrocyte and oligodendrocyte, to synthesize and secret a set of trophic factors and cytokines, to support the expansion and function of other cells, to migrate toward and home to pathological areas, and to be readily administrated with conventional methods. These cells tend to work through the following mechanisms.
These cells can differentiate into neural cells, bone, cartilage, hepatic and renal cells and can build new blood vessels thus help in regenerating the diseased or injured tissues.
Immune System Regulation
Umbilical cord derived mesenchymal stem cells possess strong anti inflammatory and immunomodulatory properties. These cells regulate the immune system and reduce inflammation which helps in treating autoimmune and other inflammatory conditions.
Umbilical cord-derived stem cells secrete a broad variety of cytokines, chemokines, and growth factors which helps these cells in homing at the injury site, stimulate the resident stem cells and promote cellular differentiation.